Publications

A full list of Karen’s publications can be found on her NCBI Bibliography.
A full list of Somen’s publications can be found on his NCBI Bibliography.

*  indicates post-doc, ** indicates graduate student, *** indicates undergraduate student, ¥ indicates international collaborator, † indicates industry collaborator

2018

  • Alam, A.***, Jiang, L.***, Kittleson, G. A.***, Steadman, K. D.***, Nandi, S., Fuqua, J. L., Palmer, K.E., Tusé D.† , and McDonald, K. A. (2018). Technoeconomic Modeling of Plant-Based Griffithsin Manufacturing. Frontiers in Bioengineering and Biotechnology, 6, 102.
    DOI: 10.3389/fbioe.2018.00102
  • Huang, Ting-Kuo**, Falk, Bryce W., Dandekar,  Abhaya M., McDonald, Karen A. (2018). Enhancement of Recombinant Protein Production in Transgenic Nicotiana benthamiana Plant Cell Suspension Cultures with Co-Cultivation of Agrobacterium Containing Silencing Suppressors. International Journal of Molecular Sciences. 2018; 19(6):1561.
    DOI: 10.3390/ijms19061561.
  • Sukenik, Sara C.**, Karuppanan, Kalimuthu*, Li, Qiongyu**, Lebrilla, Carlito B., Nandi, Somen, and McDonald, Karen A. (2018). Transient Recombinant Protein Production in Glycoengineered Nicotiana benthamiana Cell Suspension Culture. International Journal of Molecular Sciences, 19(4): 1205.
    DOI: 10.3390/ijms19041205.
  • Silberstein, David Z.**, Karuppanan Kalimuthu*, Aung, Hnin Hnin, Chen, Ching-Hsein, Cross, Carroll E., McDonald,  Karen A. (2018) An Oxidation-Resistant, Recombinant Alpha-1 Antitrypsin Produced in Nicotiana benthamiana. Free Radical Biology and Medicine 120: 303-310.
    DOI: 10.1016/j.freeradbiomed.2018.03.015.
  • Xiong, Yongao**, Li, Qiongyu**, Kailemia, Muchena J.*, Lebrilla, Carlito B., Nandi, Somen and McDonald, KarenA. (2018). Glycoform Modification of Secreted Recombinant Glycoproteins through Kifunensine Addition during Transient Vacuum Agroinfiltration. International Journal of Molecular Sciences19(3): 890.
  • Corbin, Jasmine M.**, Kailemia, Muchena J.*, Cadieux, C. Linn, AlkanaimshSalem**, Karuppanan, Kalimuthu*, Rodriguez, Raymond L., Lebrilla, Carlito B., Cerasoli, Douglas M., McDonald, Karen A. and Nandi, Somen (2018). Purification, Characterization, and N-glycosylation of Recombinant Butyrylcholinesterase from Transgenic Rice Cell Suspension Cultures. Biotechnology and Bioengineering, 115(5), 1301-1310. DOI: 10.1002/bit.26557.

2017

  • Leth, Ingrid K.** and McDonald Karen A. (2017). Growth Kinetics and Scale-up of Agrobacterium tumefaciensApplied Microbiology and Biotechnology, 101(12):4895-4903.
    DOI: 10.1007/s00253-017-8241-5
  • Leth, Ingrid K.** and McDonald K.A. (2017).  Media Development for Large Scale Agrobacterium tumefaciens Culture.” Biotechnology Progress, 33(5):1218.
    DOI: 10.1002/btpr.2504.
  • Karuppanan, Kalimuthu*, Duhra-Gill, Sifti**, Kailemia, Muchena J.*, Phu, My L., Lebrilla, Carlito B., Dandekar, Abhaya M., Rodriguez, Raymond L., Nandi, Somen and McDonald Karen A. (2017). Expression, Purification, and Biophysical Characterization of a Secreted Anthrax Decoy Fusion Protein in Nicotiana benthamianaInternational Journal of Molecular Sciences, 18(1):89.
    DOI: 10.3390/ijms18010089

2016

  • Nandi S., Kwong A.T.***, Holtz B.R., Erwin R.L., Marcel S., McDonald K.A. (2016). “Techno-economic analysis of a transient plant-based platform for monoclonal antibody production.” mAbs. 8(8):1456-1466.
    DOI: 10.1080/19420862.2016.1227901
  • Nandi, S., Thota, S.*, Nag, A.*, Divyasukhananda, S.¥, P Goswami¥, Aravindakshan, A., Rodriguez, RL., and Mukherjee, B (2016) Computing for rural empowerment: enabled by last-mile telecommunications.  IEEE Communications 54 (6), 102-109. DOI: 10.1109/MCOM.2016.7498095
  • Goswami, R.¥, Dasgupta, P.¥, Saha, S., Venkatapuram, P.***, and Nandi, S. (2016). Resource integration in smallholder farms for sustainable livelihoods in developing countries Cogent Food & Agriculture 2(1) 1-15.
    DOI: 10.1080/23311932.2016.1272151
  • Jung S.**, McDonald K.A. (2016). “Improved Transient Production of a Cellulase Enzyme in Detached Sunflower Leaves Using Plant Hormones.” Biotechnology and Bioprocess Engineering. Nov;21(6):726-732.
    DOI: 10.1007/s12257-016-0410-3
  • Alkanaimsh S.**, Karuppanan K.*, Guerrero A.*, Tu A.M., Hashimoto B.**, Hwang M.S.*, Phu M.L., Arzola L.*, Lebrilla C.B., Dandekar A.M., Falk B.W., Nandi S., Rodriguez R.L., McDonald K.A. (2016). “Transient Expression of Tetrameric Recombinant Human Butyrylcholinesterase in Nicotiana benthamiana.” Frontiers in plant science. 7:743.
    DOI: 10.3389/fpls.2016.00743
  • Corbin J.M.**, Hashimoto B.I.**, Karuppanan K.*, Kyser Z.R.***, Wu L.†, Roberts B.A.†, Noe A.R.†, Rodriguez R.L., McDonald K.A., Nandi S. (2016). “Semicontinuous Bioreactor Production of Recombinant Butyrylcholinesterase in Transgenic Rice Cell Suspension Cultures.” Frontiers in plant science. 7:412.
    DOI: 10.3389/fpls.2016.00412

2015

  • Jung S.K., McDonald K.A., Dandekar A.M. (2015). “Effect of leaf incubation temperature profiles on Agrobacterium tumefaciens-mediated transient expression.” Biotechnology progress. 31(3):783-90.
    DOI: 10.1002/btpr.2077
  • Dinh, Thu Huong ¥, Jang, Nan Young ¥, McDonald, Karen A., & Won, Keehoon ¥. (2015). Cross-linked aggregation of glutamate decarboxylase to extend its activity range toward alkaline pH. Journal of Chemical Technology & Biotechnology, 90(11), 2100-2105. (JIF: 3.10)
    DOI: 10.1002/jctb.4640
  • Nandi, S. and Khush, G.S. (2015) Strategies to Increase Heterologous Protein Expression in Rice Grains. In: Recent Advancements in Gene Expression and Enabling Technologies in Crop Plants (Azhakanandam, K., Silverstone, A., Daniell, H. and Davey, R.M. eds), pp. 241-262. New York, NY: Springer New York.
    DOI: 10.1007/978-1-4939-2202-4
  • Doyle, M.M.***, Garcia, S.**, Bahati, E.¥, Karamuzi, D.¥, Cullor, J.S. and Nandi, S. (2015) Microbiological analysis of raw milk in Rwanda. African Journal of Food Science and Technology 6, 141-143.
    DOI: 10.4315/0362-028X.JFP-13-230

2014

  • Jung S.K.**, Lindenmuth B.E.**, McDonald K.A., Hwang M.S.*, Bui M.Q., Falk B.W., Uratsu S.L., Phu M.L., Dandekar A.M. (2014). “Agrobacterium tumefaciens mediated transient expression of plant cell wall-degrading enzymes in detached sunflower leaves.” Biotechnology progress. 30(4):905-15.
    DOI: 10.1002/btpr.1888
  • Tusé D.†, Tu T.**, McDonald K.A. (2014). “Manufacturing economics of plant-made biologics: case studies in therapeutic and industrial enzymes.” BioMed research international. 2014:256135.
    DOI: 10.1155/2014/256135
  • Kingsbury N.J.**, McDonald K.A. (2014). “Quantitative evaluation of E1 endoglucanase recovery from tobacco leaves using the vacuum infiltration-centrifugation method.” BioMed research international. 2014:483596.
    DOI: 10.1155/2014/483596
  • Nandi S., McDonald K.A. (2014). “Expression of Recombinant Proteins in Plant Cell Culture.” In Hefferon K. (Ed.), Plant-derived Pharmaceuticals: Principles and Applications for Developing Countries. Boston, MA: CABI.

2013

  • Dinh T.H.¥, Ho N.A.¥, Kang T.J., McDonald K.A., Won K. ¥ (2013). “Salt-free production of γ-aminobutyric acid from glutamate using glutamate decarboxylase separated from Escherichia coli.” Journal of Chemical Technology and Biotechnology. Nov 25;89:1432-1436
    DOI: 10.1002/jctb.4251

2012

  • Hwang M.S.*, Lindenmuth B.E.**, McDonald K.A., Falk B.W. (2012). “Bipartite and tripartite Cucumber mosaic virus-based vectors for producing the Acidothermus cellulolyticus endo-1,4-beta-glucanase and other proteins in non-transgenic plants.” BMC Biotechnol. Sep 21;12(1):66.
    DOI: 10.1186/1472-6750-12-66
  • Huang T.K.**, McDonald K.A. (2012). “Bioreactor systems for in vitro production of foreign proteins using plant cell cultures.” Biotechnol Adv. Mar-Apr;30(2):398-409.
    DOI: 10.1016/j.biotechadv.2011.07.016
  • Kjelstrom J.A., McDonald K.A., Hargadon A., Agatstein W., Arnold M. (2012). “The University of California, Davis, Collaborative Model for Biotechnology Education and Training.” Journal of Commercial Biotechnology. 12(4):87-97.
  • Huang T.**, McDonald K.A. (2012). “Molecular Farming Using Bioreactor-Based Plant Cell Suspension Cultures for Recombinant Protein Production.” In Wang A., Ma S., (Eds.), Molecular Farming in Plants. New York, NY: Springer.
  • McDonald K.A. (2012). “In Planta Production of Cell Wall Degrading Enzymes.” In Kole C., Joshi C.P., Shonnard D., (Eds.), Handbook of Bioenergy Crop Plants. Boca Raton, FL: CRC Press.

2011

  • Jung S.**, McDonald K.A. (2011). “Visual Gene Developer: a fully programmable bioinformatics software for synthetic gene optimization.” BMC Bioinformatics, 12(1): 340.
    DOI: 10.1186/1471-2105-12-340
  • Arzola L.**, Chen J.***, Rattanaporn K.**, Maclean J.M.†, McDonald K.A. (2011). “Transient Co-Expression of Post-Transcriptional Gene Silencing Suppressors for Increased in Planta Expression of a Recombinant Anthrax Receptor Fusion Protein.” Int. J. Mol. Sci, 12: 4975-4990.
    DOI: 10.3390/ijms12084975
  • Lindenmuth B.E.**, McDonald K.A. (2011). “Production and characterization of Acidothermus cellulolyticus endoglucanase in Pichia pastoris.” Protein Expression and Purification, 77(2): 153-158.
    DOI: 10.1016/j.pep.2011.01.006
  • McDonald K.A. (2011). “Bioreactions and Bioreactor Operation: Heterologous Protein Expression.” In Moo-Young M. (Ed.), Comprehensive Biotechnology. Waltham, MA: Elsevier.

2010

  • Huang T.K.**, Plesha M.A.**, McDonald K.A. (2010). “Semicontinuous Bioreactor Production of a Recombinant Human Therapeutic Protein Using a Chemically Inducible Viral Amplicon Expression System in Transgenic Plant Cell Suspension Cultures.” Biotechnology and Bioengineering, 106(3): 408-421.
    DOI: 10.1002/bit.22713

2009

  • Huang T.K.**, McDonald K.A.  (2009). “Bioreactor Engineering for Recombinant Protein Production in Plant Cell Suspension Cultures.” Biochemical Engineering Journal, 45: 168-184.
    DOI: 10.1016/j.bej.2009.02.008
  • Plesha M.A.**, Huang T.K.**, Dandekar A.M., Falk B.W., McDonald K.A. (2009). “Optimization of the Bioprocessing Conditions for Scale-Up of Transient Production of a Heterologous Protein in Plants Using a Chemically Inducible Viral Amplicon Expression System.” Biotechnology Progress, 25(3): 722-734.
    DOI: 10.1002/btpr.149
  • Huang T.K.**, Plesha M.A.**, Falk B.W., Dandekar A.M., McDonald K.A. (2009). “Bioreactor Strategies for Improving Production Yield and Functionality of a Recombinant Human Protein in Transgenic Tobacco Cell Cultures.” Biotechnology and Bioengineering, 102(2): 508-520.
    DOI: 10.1002/bit.22061

2007

  • Plesha M.A.**, Huang T.K.**, Dandekar A.M., Falk B.W., McDonald K.A. (2007). “High-Level Transient Production of a Heterologous Protein in Plants by Optimizing Induction of a Chemically Inducible Viral Amplicon Expression System” Biotechnology Progress, 23(6): 1277-1285.
    DOI: 10.1021/bp070238s
  • Zapalac E.**, McDonald K.A. (2007). “Economic and Environmental Assessment of the Purification of Alpha-1-Antitrypsin from Transgenic Plant Cell Suspension Cultures.” In Heinzle E., Biwer A. (Eds.), Development of Sustainable Bioprocesses – Modeling and Assessment. (pp. 261-270). Hoboken, NJ: Wiley.